Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Testing evidence
Evidence status
Recognised certification
Manufacturer statement
NSF Certified for Sport registry entry for Sports Research® (product listing shown as "Creatine Monohydrate Unflavored" with brand Sports Research® and website www.sportsresearch.com) confirms a Sports Research product is certified in NSF's own registry.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Testing evidence
Evidence status
Recognised certification
Manufacturer statement
NSF Certified for Sport registry entry for Sports Research® (product listing shown as "Creatine Monohydrate Unflavored" with brand Sports Research® and website www.sportsresearch.com) confirms a Sports Research product is certified in NSF's own registry.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Compare the labelled daily biotin in mcg. The 50 mcg UK label NRV explains label percentages and is not a target supplement dose. Higher-dose products can interfere with some blood tests, so tell a clinician if you take biotin before testing. Where directions give a range, the range is shown and daily cost uses the low end (no directions: one unit a day). Read the dose guide ↓
NSF Certified for Sport registry entry for Sports Research® (product listing shown as "Creatine Monohydrate Unflavored" with brand Sports Research® and website www.sportsresearch.com) confirms a Sports Research product is certified in NSF's own registry.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nutricost product page says: “Nutricost Biotin is Non-GMO, Gluten Free, and 3rd Party Tested” and “Nutricost products are tested by an independent, accredited lab to help verify that what’s on the label is what’s in the bottle.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon listing image/text shows “Non-GMO Verified,” “Vegan Certified,” and “Third Party Tested”; NSF registry independently confirms a Sports Research product listing with NSF Certified for Sport® (though for Creatine Monohydrate Unflavored, not this biotin product). For this biotin product specifically, Sports Research’s own product page says “Third Party Tested Certified” and shows an NSF logo, but I did not find an NSF registry page for this exact biotin item.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer site says: "Every product manufactured by Bronson is put through a rigorous process to ensure purity, potency and integrity" and "From raw materials to finished batches, Bronson supplements undergo numerous laboratory tests to ensure quality standards are met."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nutricost’s product page says: “Nutricost Biotin is Non-GMO, Gluten Free, and 3rd Party Tested” and “Nutricost products are tested by an independent, accredited lab to help verify that what’s on the label is what’s in the bottle.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Country Life’s own site says: “Our manufacturing facility maintains strict quality control standards and was an early adopter of NSF’s third party GMP certification” and “Non-GMO Project Verification Across Our Product Line” plus “Every ingredient and formula undergo multiple layers of testing to confirm purity, potency, and accuracy.” The product page also shows “Certified Gluten-Free” and the Amazon image shows a Non-GMO Project Verified seal, but I did not find an independently verified registry page for this specific biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon image text and NOW product page say the product is "Made and quality tested in the USA with globally sourced ingredients" and NOW's quality page says "Intertek GMP Supplement Certification" applies to NOW's manufacturing process, but I did not find an independently verifiable product-specific COA or certification for this biotin item.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nature's Bounty says: "Every Nature’s Bounty® product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and full potency. As an added measure of quality assurance, the initial ingredients, as well as the final product are tested in our microbiological laboratory to make certain that the product is pure and free of harmful bacteria." The same page also says its facilities were audited by USP and STR, but I did not find an independently verifiable registry or product-specific certificate for this biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Bronson’s own Certifications page says: “Every product manufactured by Bronson is put through a rigorous process to ensure purity, potency and integrity… Bronson products consistently comply… to deliver premium supplements verified for quality and safety” and “From raw materials to finished batches, Bronson supplements undergo numerous laboratory tests to ensure quality standards are met.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Natrol’s quality page says: “Every lot of finished products as part of our quality control process is tested to ensure safety, quality, strength, composition, and consistency.” It also says Natrol enlists NSF International to review its manufacturing facilities and processes annually for GMP compliance.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon listing only shows manufacturing/quality marketing: "High Quality - our supplements manufactured in the UK under GMP (Good Manufacturing Practice) in an ISO accredited facility"; I did not find any actual claim that this specific biotin product was tested, verified, or certified by a third party, nor any independent registry match or COA.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nature's Bounty says on its About Us page: "Every product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and potency." It also says: "Every single month. We test and retest to bring you potent and efficacious ingredients, guaranteed."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Thorne’s product page for Biotin states: “This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer states: "All raw materials and finished products are independently tested for purity and potency by our third-party laboratories" and the UK site says "All production lots are tested by accredited and cGMP compliant laboratories."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
NSF listing for Amazon.com Services, LLC shows certified finished products including “Amazon Elements Biotin Gummies” under NSF/ANSI Standard 173 Dietary Supplements.
Laboratory
Not recorded
Certification body
Not recorded
Batch
Not recorded
Batch-specific report
Not established in this record
Report date
Not recorded
Evidence checked
2026-09-27 16:33:20
Why this score?
Testing & evidence
4/20
Ingredient/formulation quality
17/25
Value
16/20
Dose transparency
10/15
Manufacturer transparency
9/10
Label/ingredient transparency
9/10
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Doctor's Best says on its About Us page: "Composition is everything, and we stand behind what’s in our products–always." and "every product is backed by research."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
NOW’s product page says: “Made and quality tested in the USA with globally sourced ingredients.” The same page also links to “Intertek GMP Supplement Certification,” but I did not find a product-specific independent registry entry or COA for this biotin item.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nature’s Bounty says on its own site that “Every product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and potency” and that “Every single month. We test and retest to bring you potent and efficacious ingredients, guaranteed.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
USP Verified Products registry lists “Nature Made Biotin 1000 Mcg Softgels” under Nature Made / Softgels / Vitamin, and USP’s own page explains that the USP Verified Mark indicates the product contains the ingredients listed on the label in declared potency, does not contain harmful levels of specified contaminants, and has been tested against performance standards.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
NSF Certified for Sport registry entry for Sports Research® (product listing shown as "Creatine Monohydrate Unflavored" with brand Sports Research® and website www.sportsresearch.com) confirms a Sports Research product is certified in NSF's own registry.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nutricost product page says: “Nutricost Biotin is Non-GMO, Gluten Free, and 3rd Party Tested” and “Nutricost products are tested by an independent, accredited lab to help verify that what’s on the label is what’s in the bottle.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon listing image/text shows “Non-GMO Verified,” “Vegan Certified,” and “Third Party Tested”; NSF registry independently confirms a Sports Research product listing with NSF Certified for Sport® (though for Creatine Monohydrate Unflavored, not this biotin product). For this biotin product specifically, Sports Research’s own product page says “Third Party Tested Certified” and shows an NSF logo, but I did not find an NSF registry page for this exact biotin item.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer site says: "Every product manufactured by Bronson is put through a rigorous process to ensure purity, potency and integrity" and "From raw materials to finished batches, Bronson supplements undergo numerous laboratory tests to ensure quality standards are met."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nutricost’s product page says: “Nutricost Biotin is Non-GMO, Gluten Free, and 3rd Party Tested” and “Nutricost products are tested by an independent, accredited lab to help verify that what’s on the label is what’s in the bottle.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Country Life’s own site says: “Our manufacturing facility maintains strict quality control standards and was an early adopter of NSF’s third party GMP certification” and “Non-GMO Project Verification Across Our Product Line” plus “Every ingredient and formula undergo multiple layers of testing to confirm purity, potency, and accuracy.” The product page also shows “Certified Gluten-Free” and the Amazon image shows a Non-GMO Project Verified seal, but I did not find an independently verified registry page for this specific biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon image text and NOW product page say the product is "Made and quality tested in the USA with globally sourced ingredients" and NOW's quality page says "Intertek GMP Supplement Certification" applies to NOW's manufacturing process, but I did not find an independently verifiable product-specific COA or certification for this biotin item.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nature's Bounty says: "Every Nature’s Bounty® product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and full potency. As an added measure of quality assurance, the initial ingredients, as well as the final product are tested in our microbiological laboratory to make certain that the product is pure and free of harmful bacteria." The same page also says its facilities were audited by USP and STR, but I did not find an independently verifiable registry or product-specific certificate for this biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Bronson’s own Certifications page says: “Every product manufactured by Bronson is put through a rigorous process to ensure purity, potency and integrity… Bronson products consistently comply… to deliver premium supplements verified for quality and safety” and “From raw materials to finished batches, Bronson supplements undergo numerous laboratory tests to ensure quality standards are met.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Natrol’s quality page says: “Every lot of finished products as part of our quality control process is tested to ensure safety, quality, strength, composition, and consistency.” It also says Natrol enlists NSF International to review its manufacturing facilities and processes annually for GMP compliance.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon listing only shows manufacturing/quality marketing: "High Quality - our supplements manufactured in the UK under GMP (Good Manufacturing Practice) in an ISO accredited facility"; I did not find any actual claim that this specific biotin product was tested, verified, or certified by a third party, nor any independent registry match or COA.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nature's Bounty says on its About Us page: "Every product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and potency." It also says: "Every single month. We test and retest to bring you potent and efficacious ingredients, guaranteed."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Thorne’s product page for Biotin states: “This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer states: "All raw materials and finished products are independently tested for purity and potency by our third-party laboratories" and the UK site says "All production lots are tested by accredited and cGMP compliant laboratories."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
NSF listing for Amazon.com Services, LLC shows certified finished products including “Amazon Elements Biotin Gummies” under NSF/ANSI Standard 173 Dietary Supplements.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Doctor's Best says on its About Us page: "Composition is everything, and we stand behind what’s in our products–always." and "every product is backed by research."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
NOW’s product page says: “Made and quality tested in the USA with globally sourced ingredients.” The same page also links to “Intertek GMP Supplement Certification,” but I did not find a product-specific independent registry entry or COA for this biotin item.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nature’s Bounty says on its own site that “Every product is subjected to numerous quality tests and assays throughout the manufacturing process to verify purity and potency” and that “Every single month. We test and retest to bring you potent and efficacious ingredients, guaranteed.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
USP Verified Products registry lists “Nature Made Biotin 1000 Mcg Softgels” under Nature Made / Softgels / Vitamin, and USP’s own page explains that the USP Verified Mark indicates the product contains the ingredients listed on the label in declared potency, does not contain harmful levels of specified contaminants, and has been tested against performance standards.
One-time purchase prices; delivery and conditional discounts excluded. Daily cost uses the recorded label serving. Comparison amounts are not personal dose recommendations. Unknown Prime eligibility is not treated as confirmed.
Biotin forms and labels explained
Most ordinary biotin products contain the same nutrient at very different doses. Compare the daily micrograms, blend composition, format and evidence rather than assuming a higher dose or a particular delivery form is better.
Biotin
Vitamin B7
Canonical unit
mcg
Adult AI
30 mcg/day
The AI describes nutritional adequacy; it is not a target high-dose supplement serving.
Biotin in a blend
Multi-ingredient formula
Compare
Each active separately
Do not infer
Blend effect = biotin effect
Other vitamins, minerals and branded ingredients need their own doses and evidence.
High-dose biotin
Dose context, not a new form
5 mg
5,000 mcg
Key issue
Lab-test interference
A high dose does not establish better hair or nail results and may be relevant to laboratory testing.
Biotin dose: US intake references and high-dose context
For US adults aged 19+, the National Academies' Adequate Intake (AI) is 30 mcg/day; lactation uses 35 mcg/day. An AI is used because the evidence was insufficient to establish an EAR and RDA. [1]
FDA's Daily Value is also 30 mcg for adults and children aged 4+, which is a labelling reference. [2] Neither figure means that a supplement providing thousands of micrograms is more effective.
Keep comparisons in micrograms. 1 mg equals 1,000 mcg, so a 5 mg product provides 5,000 mcg. No tolerable upper intake level has been established by the Food and Nutrition Board, but that absence should not be presented as evidence of unlimited safety. [1]
What the evidence says about biotin
Biotin deficiency can cause hair, skin and nail changes, but deficiency evidence should not be generalized to healthy adults. NIH ODS describes the evidence for hair, skin and nail supplementation as limited. [1] A 2024 review found only three eligible oral-biotin hair studies; the highest-quality placebo-controlled study found no difference between biotin and placebo. [5]
Older brittle-nail evidence used 2.5 mg/day and reported improvement among many evaluable participants, but the study lacked a placebo control and had substantial attrition. [6]
Biotin evidence by goal
Evidence by goal
Goal
Evidence strength
What was assessed
Typical study context
Main limitation
Hair growth without known deficiency
Weak / insufficient
Oral biotin across three eligible studies in a 2024 review
The highest-quality placebo-controlled study found no difference; other studies involved selected clinical populations.
Very limited evidence base and poor generalisability to healthy shoppers.
Brittle nails
Limited, low-certainty
Oral biotin 2.5 mg/day
Older study with 71 treated and 45 evaluable participants; mean treatment around 5.5 months.
No placebo group, attrition and old evidence.
Avoiding lab-test errors
Well-established analytical risk
5–10 mg/day oral biotin and biotin-sensitive immunoassays
Small human studies across multiple assay platforms.
Interference varies by assay, manufacturer, dose and time; no universal washout interval.
Read the full evidence-by-goal detail
Hair growth
High-quality evidence does not currently support routine biotin supplementation for hair growth in people without a demonstrated deficiency. [5]
Nails
Small, older uncontrolled studies suggest possible benefit for brittle nails, but they do not establish a benefit for normal nails or justify choosing the highest-dose product. [6]
Correcting deficiency
Biotin is an essential nutrient and deficiency can cause clinical problems, but deficiency is rare in healthy people consuming mixed diets. [1] Suspected deficiency should not be reduced to retail dose ranking.
When to take biotin
No reviewed source establishes a universal morning-versus-evening advantage for ordinary biotin supplementation. Follow the product label unless a clinician gives different instructions. For blood tests, timing matters because circulating biotin can interfere with some assays. The required abstention period varies by dose, test and assay platform, so follow instructions from the ordering clinician or laboratory rather than a generic internet rule. [4][12]
Biotin safety and blood-test interference
Who should be cautious?If any of the following apply to you, speak to a healthcare professional before taking Biotin - see the full detail below for why.
People having thyroid, cardiac, hormone or other laboratory immunoassays
People using high-dose products in the milligram range
People whose treatment decisions depend on laboratory results
Pregnant or breastfeeding people should use clinician-led advice rather than extrapolating from general high-dose beauty products
The Food and Nutrition Board did not establish a UL for biotin because available data were insufficient to identify toxicity at high intakes. [1] This should be stated as 'no UL established', not 'no upper limit' or 'safe at any dose'.
FDA warns that biotin can significantly interfere with certain laboratory tests and has continued to highlight falsely low troponin results as a safety concern. [3] A small human study using 10 mg/day for one week found interference in some, but not all, biotinylated immunoassays. [7] The affected tests and duration vary by platform and dose. [4][12]
Biotin in hair, skin and nail blends
Hair, skin and nail products often combine biotin with other vitamins, minerals or branded ingredients. Record every active separately. Evidence for another ingredient cannot be credited to biotin, and a multi-ingredient label makes it harder to identify which ingredient caused an effect or adverse reaction. FDA requires Supplement Facts labels to identify dietary ingredients and amounts per serving. [11]
Who might consider biotin
Biotin supplementation has a clear nutritional role when intake or deficiency is genuinely a concern, but true deficiency is rare. [1] People considering biotin mainly for hair or nails should know that evidence in non-deficient adults is limited. People expecting laboratory testing should disclose biotin-containing supplements to the clinician or laboratory because results can be distorted. [3]
How to compare biotin testing evidence
For biotin products, look for evidence that confirms identity, potency/strength, composition and relevant contaminants for the exact finished product. FDA dietary-supplement CGMP rules address these quality controls. [9]
Independent programs such as USP Verification can add evidence through facility auditing, documentation review and product testing, but verification does not prove that biotin will deliver a cosmetic outcome. [10] A manufacturer's 'third-party tested' statement should remain distinct from a verifiable product certification or batch report.
Blood testing & your results
Biotin can interfere with laboratory assays that use biotin-streptavidin technology. FDA has warned about incorrect results, including falsely low troponin values. [3] In a six-person study, 10 mg/day for seven days interfered with 9 of 23 biotinylated assays but none of 14 non-biotinylated controls. [7] Other studies show the duration of thyroid-test interference differs by dose and assay platform. [12] Tell the clinician or laboratory what you take and use their test-specific instructions; there is no single washout time that fits every assay.
Testing evidence in this comparison
A testing claim is not the same as a verified report. No public evidence located does not mean a product has not been tested.
Testing review pending0
Recognised certification2
Verified independent evidence0
Manufacturer COA0
Testing claimed14
No public evidence located9
What does biotin cost?
Current US comparison set, based on the daily serving shown on each label.
$0.03Lowest daily cost
$0.10Median daily cost
$0.47Highest daily cost
Your questions, answered
How much biotin do adults need in the US?
The adult Adequate Intake is 30 mcg/day, and FDA's Daily Value is also 30 mcg for adults and children aged 4+. [1][2] These references do not mean that everyone needs a separate 30 mcg supplement.
Is 5,000 mcg of biotin a high dose?
It is 5 mg, far above the 30 mcg adult AI/DV. Current commercial products do use 5,000 mcg servings, but a retail serving is not an evidence-based target. [8]
Does biotin help hair growth?
Evidence in people without biotin deficiency is weak. A 2024 review found only three eligible oral-biotin studies and did not find high-quality support for routine hair supplementation. [5]
Can biotin interfere with blood tests?
Yes. FDA warns that biotin can produce incorrect results in certain laboratory tests, including some troponin assays. [3] The affected tests and timing vary, so tell the clinician or lab what you take.
Does biotin have an upper limit?
The Food and Nutrition Board did not establish a tolerable upper intake level for biotin because the available evidence was insufficient. [1] This is not proof that any dose is safe, particularly because high supplemental doses can interfere with laboratory testing.