Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Testing evidence
Evidence status
Verified independent evidence
Manufacturer statement
Manufacturer page says "Independently Lab Tested" and links to a certificate; the certificate reads "CERTIFICATE OF ANALYSIS" for "Sample Description Natures Zest Biotin Complex" and lists microbiological results.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Testing evidence
Evidence status
Verified independent evidence
Manufacturer statement
Manufacturer page says "Independently Lab Tested" and links to a certificate; the certificate reads "CERTIFICATE OF ANALYSIS" for "Sample Description Natures Zest Biotin Complex" and lists microbiological results.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Compare the labelled daily biotin in mcg. The 50 mcg UK label NRV explains label percentages and is not a target supplement dose. Higher-dose products can interfere with some blood tests, so tell a clinician if you take biotin before testing. Where directions give a range, the range is shown and daily cost uses the low end (no directions: one unit a day). Read the dose guide ↓
Manufacturer page says "Independently Lab Tested" and links to a certificate; the certificate reads "CERTIFICATE OF ANALYSIS" for "Sample Description Natures Zest Biotin Complex" and lists microbiological results.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
VitaBright’s own product page says: “Who performs your testing, an in-house lab or an independent third party?” and “Do you have a Certificate of Analysis (CoA) for your products or their ingredients?” The page also says the brand has a “Product Testing and Quality Controls” article, but I did not find a product-specific CoA, lab report, or certifying-body registry entry for this biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
WeightWorld product page says: "Third-party lab-tested for pesticides and heavy metals to ensure purity and potency" and also shows "10/10 TESTS PASSED / 3/3 CLAIMS VERIFIED / INDEPENDENTLY LAB-TESTED / SEE LAB RESULTS".
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon listing and Igennus product page both say the product is "lab verified" / "PURE & CLEAN - we use hypoallergenic and lab-verified ingredients" and the Amazon bullets say "lab verified" and "GMP manufactured in the UK & lab verified to ensure the highest quality." I found no independently verifiable COA or registry entry for this specific biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nutricost product page says: “Nutricost Biotin is Non-GMO, Gluten Free, and 3rd Party Tested” and “Nutricost products are tested by an independent, accredited lab to help verify that what’s on the label is what’s in the bottle.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer site says: "To ensure the highest safety and quality, our products undergo rigorous testing for heavy metals and unwanted compounds during production to fully comply with global regulations."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Healthspan’s own site says the product is a “high strength vegan formulation” and that it contains “1000 µg biotin”; Healthspan Elite also says “Informed Sport assures athletes that products bearing its logo are regularly tested for banned substances,” but I did not find an independent registry page confirming this specific biotin product is certified.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer page says "Independently Lab Tested" and links to a certificate; the certificate reads "CERTIFICATE OF ANALYSIS" for "Sample Description Natures Zest Biotin Complex" and lists microbiological results.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
VitaBright’s own product page says: “Who performs your testing, an in-house lab or an independent third party?” and “Do you have a Certificate of Analysis (CoA) for your products or their ingredients?” The page also says the brand has a “Product Testing and Quality Controls” article, but I did not find a product-specific CoA, lab report, or certifying-body registry entry for this biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
WeightWorld product page says: "Third-party lab-tested for pesticides and heavy metals to ensure purity and potency" and also shows "10/10 TESTS PASSED / 3/3 CLAIMS VERIFIED / INDEPENDENTLY LAB-TESTED / SEE LAB RESULTS".
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Amazon listing and Igennus product page both say the product is "lab verified" / "PURE & CLEAN - we use hypoallergenic and lab-verified ingredients" and the Amazon bullets say "lab verified" and "GMP manufactured in the UK & lab verified to ensure the highest quality." I found no independently verifiable COA or registry entry for this specific biotin product.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Nutricost product page says: “Nutricost Biotin is Non-GMO, Gluten Free, and 3rd Party Tested” and “Nutricost products are tested by an independent, accredited lab to help verify that what’s on the label is what’s in the bottle.”
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Manufacturer site says: "To ensure the highest safety and quality, our products undergo rigorous testing for heavy metals and unwanted compounds during production to fully comply with global regulations."
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
Healthspan’s own site says the product is a “high strength vegan formulation” and that it contains “1000 µg biotin”; Healthspan Elite also says “Informed Sport assures athletes that products bearing its logo are regularly tested for banned substances,” but I did not find an independent registry page confirming this specific biotin product is certified.
Displayed points and weights are rounded; the total uses unrounded weights. Pending dimensions are excluded. Provisional scores may change after review.
One-time purchase prices; delivery and conditional discounts excluded. Daily cost uses the recorded label serving. Comparison amounts are not personal dose recommendations. Unknown Prime eligibility is not treated as confirmed.
Biotin forms and labels explained
Biotin products differ more by dose, blend composition and physical format than by a proven hierarchy of chemical forms. Keep the label amount in micrograms and separate biotin from other actives.
D-biotin
Biotin ingredient identity
GB-listed form
D-biotin
Dose unit
mcg
The GB register lists D-biotin. Disclosure of the full name does not by itself prove superior absorption or results.
Biotin in a blend
Multi-ingredient formula
Compare
Biotin separately
Also record
Other actives
Zinc, selenium and other ingredients need their own amounts and evidence; do not attribute the blend's claims to biotin alone.
High-dose biotin
Dose context, not a new form
1 mg
1,000 mcg
Key issue
Lab-test interference
A larger number is not automatically better. High-dose products need explicit blood-test interference context.
Biotin dose: UK label references and high-dose context
The UK adult biotin Nutrient Reference Value used on labels is 50 mcg. [2] This figure is useful for understanding label percentages, but it is not a personal supplement prescription.
The NHS does not set a numeric adult daily requirement on its biotin guidance. It says people should be able to get the biotin they need from a varied, balanced diet and that taking 0.9 mg (900 mcg) or less per day from supplements is unlikely to cause harm. [1] That 900 mcg statement is safety context, not an intake target and not a formal upper limit.
For comparison, keep all products in micrograms: 1 mg equals 1,000 mcg. A 5 mg label therefore provides 5,000 mcg. Do not treat a larger number as evidence of better results.
What the evidence says about biotin
Biotin deficiency can affect hair, skin and nails, but this does not mean extra biotin improves them in people who are not deficient. A 2024 review found only three eligible studies of oral biotin for hair growth; the highest-quality placebo-controlled study found no difference between biotin and placebo, and the remaining studies involved selected clinical populations. [5]
Evidence for brittle nails is also limited. An older uncontrolled report used 2.5 mg (2,500 mcg) per day and reported improvement among many evaluable participants, but the lack of a placebo group, attrition and age of the study limit what can be concluded for typical shoppers. [8]
Biotin evidence by goal
Evidence by goal
Goal
Evidence strength
What was assessed
Typical study context
Main limitation
Hair growth in adults without known deficiency
Weak / insufficient
Oral biotin across three eligible studies in a 2024 review
The highest-quality placebo-controlled study found no difference; the other studies used selected clinical populations.
Very small and heterogeneous evidence base; deficiency findings do not establish benefit in replete adults.
Brittle nails
Limited, low-certainty
Oral biotin 2.5 mg/day
Older clinical report; 71 treated and 45 evaluable, with mean treatment around 5.5 months.
No placebo control, attrition and old evidence; not proof for healthy nails.
Avoiding misleading blood-test results
Well-established analytical risk
High-dose oral biotin and biotin-sensitive immunoassays
Human and laboratory guidance show dose-, test- and platform-dependent interference.
Not every assay is affected and there is no single universal washout interval.
Read the full evidence-by-goal detail
Hair growth
Evidence for routine biotin supplementation in people without a demonstrated deficiency is weak. Deficiency can cause hair changes, but deficiency evidence should not be turned into a general hair-growth claim. [5][6]
Nails
Small, older uncontrolled studies suggest possible benefit in brittle-nail populations, but they do not establish that high-dose biotin strengthens normal nails in everyone. [8]
Correcting deficiency
True biotin deficiency is uncommon, and suspected deficiency is a clinical question rather than a reason to rank ordinary retail products by the highest dose. [6]
When to take biotin
No source reviewed established a universal morning-versus-evening advantage for ordinary biotin supplements. Follow the product's labelled directions unless a healthcare professional gives different instructions. The more important timing issue is laboratory testing: biotin can interfere with some immunoassays, so tell the clinician or laboratory what you take before a test and follow their test-specific instructions. [3][7]
Biotin safety and blood-test interference
Who should be cautious?If any of the following apply to you, speak to a healthcare professional before taking Biotin - see the full detail below for why.
People having thyroid, cardiac, hormone or other immunoassay-based laboratory tests
People taking very high-dose biotin products
People being investigated or treated for a medical condition where laboratory results affect decisions
Pregnant or breastfeeding people should use clinician-led advice rather than extrapolating from general retail products
The NHS says there is not enough evidence to know the effects of high daily doses of biotin supplements and describes 0.9 mg (900 mcg) or less per day from supplements as unlikely to cause harm. [1] European upper-level tables state that there are not adequate data to derive a biotin UL. [4] The absence of a formal UL is not evidence that unlimited intake is safe.
A separate risk is laboratory-test interference. The MHRA warns that biotin can interfere with thyroid immunoassays and may produce falsely high or falsely low results, with greater risk at higher doses. [3] Laboratory guidance shows that susceptibility varies by assay and manufacturer, so this page should not give one universal 'stop biotin for X hours' rule. [7]
Biotin in hair, skin and nail blends
Many hair, skin and nail products combine biotin with zinc, selenium, vitamins or other ingredients. Compare each active separately. A blend does not make the biotin dose more effective, and benefits supported for another ingredient should not be attributed to biotin. UK food-supplement guidance also distinguishes food supplements from medicines and does not permit them to be sold as disease treatments. [10]
Who might consider biotin
The clearest role for biotin supplementation is where intake or deficiency is a genuine concern assessed in context. Deficiency itself is uncommon in healthy people eating a mixed diet. [6] People shopping mainly for hair or nail benefits should know that evidence in non-deficient adults is limited. Anyone having blood tests should disclose biotin use because it can distort some results. [3]
How to compare biotin testing evidence
For biotin, useful product evidence confirms that the finished product contains the declared ingredient and amount and identifies what contaminants or other quality attributes were checked. A generic 'third-party tested' statement is weaker than a traceable report or certification record tied to the exact product. The Supplement Compare's testing guide explains these evidence levels. Read the guide
Do not treat a GMP statement as batch-specific potency evidence, and do not treat a testing badge as proof that biotin will improve hair, skin or nails.
Blood testing & your results
Biotin is unusually relevant to blood testing because it can interfere with some streptavidin-biotin immunoassays. In the UK, the MHRA specifically warns about thyroid-function tests and advises healthcare professionals to ask about biotin intake. [3] Interference depends on the dose, assay design, platform and timing. Laboratory guidance therefore supports test-specific advice rather than one universal washout interval. [7] Tell the clinician or laboratory about all biotin-containing supplements before testing.
Testing evidence in this comparison
A testing claim is not the same as a verified report. No public evidence located does not mean a product has not been tested.
Testing review pending0
Recognised certification0
Verified independent evidence1
Manufacturer COA0
Testing claimed9
No public evidence located15
What does biotin cost?
Current UK comparison set, based on the daily serving shown on each label.
£0.02Lowest daily cost
£0.07Median daily cost
£0.34Highest daily cost
Your questions, answered
How much biotin do I need in the UK?
The NHS does not give a numeric adult daily requirement for biotin and says a varied, balanced diet should provide what is needed. [1] The 50 mcg figure on UK labels is the Nutrient Reference Value used for labelling, not a personal supplement prescription. [2]
Is 10,000 mcg of biotin the same as 10 mg?
Yes. 1 mg equals 1,000 mcg, so 10 mg equals 10,000 mcg. The conversion is arithmetic; it does not imply that 10 mg is an appropriate dose.
Does biotin make hair grow faster?
Evidence in people without biotin deficiency is weak. A 2024 review found only three eligible oral-biotin hair studies and concluded that high-quality evidence does not support routine biotin as a hair supplement. [5]
Can biotin affect thyroid blood tests?
Yes. The MHRA warns that biotin can interfere with thyroid immunoassays and can produce falsely high or falsely low results. [3] Tell the clinician or laboratory what you take before testing rather than relying on a universal stop-taking interval.
Is there a safe upper limit for biotin?
No formal tolerable upper intake level has been established from the reviewed European evidence because adequate data were not available. [4] That does not mean unlimited doses are proven safe.