Igennus Super B12 Complex 1000µg
- Testing & evidence
- 21/25
- Ingredient/formulation quality
- 15/20
- Value
- 13/20
- Dose transparency
- 12/15
- Manufacturer transparency
- 6/10
- Label/ingredient transparency
- 9/10
The US version of The Supplement Compare is currently being prepared and will be available soon.
Compare UK vitamin B12 supplements by disclosed form, daily micrograms, delivery format and price. Explore methylcobalamin, cyanocobalamin and mixed forms, with guidance on vegan diets, deficiency and blood tests.
We may earn a commission from qualifying purchases at no extra cost to you. Affiliate relationships never determine our scores or rankings.
Daily B12 and daily cost use the same recorded label serving. µg and mcg both mean micrograms; 1 mg = 1,000µg. Dietary requirements, label NRV and deficiency treatment are different contexts. Neither a larger dose nor a particular form automatically earns a higher score. Read the dose guide ↓
| # | Product | B12 form | Daily dose | Price/day | Testing | Score |
|---|---|---|---|---|---|---|
| 1 | Igennus Super B12 Complex 1000µg180 sublingual tablets | Sublingual tablet | 1,000µgAbove typical supplemented range | £0.08per day£14.44 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 2 | Igennus Super B12 Complex Spray 5000µg15 ml · 45 servings | Spray | 5,000µgAbove typical supplemented range | £0.38per day£16.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 3 | WeightWorld Vitamin B12 1000µg450 tablets | Tablet | 1,000µgAbove typical supplemented range | £0.02per day£8.49 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 4 | Health4All Cyanocobalamin B12 50µg180 tablets | Tablet | 50µgWithin typical supplemented range1-tablet basis | £0.06per day£9.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 5 | Zipvit Vitamin B12 1100µg360 tablets | Tablet | 1,100µgAbove typical supplemented range | £0.02per day£8.49 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 6 | Nutravita Vitamin B12 1000µg365 tablets | Tablet | 1,000µgAbove typical supplemented range | £0.02per day£8.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 7 | Nutrition Geeks B12 Dual Power 1000µg365 tablets | Tablet | 1,000µgAbove typical supplemented range | £0.02per day£8.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 8 | Solgar Vitamin B12 100µg100 tablets | Tablet | 100µgWithin typical supplemented range | £0.07per day£6.80 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 9 | Apollo’s Hegemony Hydroxo + Adenosyl B12120 tablets · 480 servings | Tablet | 100µgWithin typical supplemented range¼ tablet daily | £0.03per day£13.59 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 10 | Natures Aid Sublingual B12 1000µg90 sublingual tablets | Sublingual tablet | 1,000µgAbove typical supplemented range | £0.08per day£7.40 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 11 | Natures Aid B12 Oral Spray 1000µg30 ml · 120 servings | Spray | 1,000µgAbove typical supplemented range | £0.07per day£8.40 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 12 | Viridian High Potency B12 1000µg60 capsules | Capsule | 1,000µgAbove typical supplemented range | £0.23per day£13.75 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 13 | Solgar Sublingual B12 1000µg250 sublingual tablets | Sublingual tablet | 1,000µgAbove typical supplemented range | £0.11per day£26.69 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 14 | HealthAid B12 Prolonged Release 1000µg100 tablets | Tablet | 1,000µgAbove typical supplemented range1-tablet basis | £0.13per day£12.91 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 15 | Horbäach B12 Liquid Drops 3000µg30 ml | Liquid | 3,000µgAbove typical supplemented range | £0.16per day£9.49 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 16 | Epigenetics Adenosyl B12 1000µg60 capsules | Capsule | 1,000µgAbove typical supplemented range | £0.37per day£21.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 17 | Vivo Life B12 Complex 500µg60 ml | Liquid | 500µgAbove typical supplemented range | £0.28per day£16.93 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 18 | Horbäach B12 Gummies 2000µg60 gummies | Gummy | 2,000µgAbove typical supplemented range | £0.30per day£8.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 19 | Novomins B12 + B Complex Gummies60 gummies | Gummy | 1,000µgAbove typical supplemented range | £0.67per day£19.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 20 | Pure Encapsulations Adenosyl/Hydroxy B1290 capsules | Capsule | 2,000µgAbove typical supplemented range | £0.37per day£33.35 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 21 | Nature Provides Liquid B12 3000µg50 ml | Liquid | 3,000µgAbove typical supplemented range | £0.49per day£24.53 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 22 | Mayfair B12 + Folic Acid — serving clarification200 tablets | Tablet | 1,000µgAbove typical supplemented range | £0.09per day£17.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 23 | PuroSure Cyanofit B12 — dose clarification50 tablets | Tablet | 50µgWithin typical supplemented range | £0.09per day£4.49 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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| 24 | Epigenetics Hydroxo B12 1 mg60 capsules | Capsule | 1,000µgAbove typical supplemented range | £0.37per day£21.99 per packBuy Nowon Amazon | Testing evidence
| Why this score?
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One-time purchase prices; delivery and conditional discounts excluded. Daily cost uses the recorded label serving. Comparison amounts are not personal dose recommendations. Unknown Prime eligibility is not treated as confirmed.
These are ingredient identities, not a ranking of absorption. Click a form in the comparison to return to its card. A disclosed chemical form is separate from whether the whole product is vegan or its contents have been independently tested.
A coenzyme form of B12
A common retail form. An active-form label alone does not establish a better clinical outcome or make a particular high dose necessary.
A form the body converts
Its name should not be used to imply a retail product is ineffective. The reason for supplementation, dose and ability to absorb B12 matter more than marketing language.
Also written hydroxycobalamin
Hydroxocobalamin is used in UK injectable treatment. That does not make an oral hydroxo capsule interchangeable with prescribed injections.
A coenzyme form of B12
A blend containing adenosyl and methyl B12 does not prove that everyone needs both in a supplement. Individual form amounts are shown only where disclosed.
More than one B12 ingredient
A 1,000µg three-form product does not supply 1,000µg of every ingredient. We do not divide a total into assumed equal shares.
Reading B12 units
B12 is recorded in micrograms. The table shows one daily amount so a 1 mg headline cannot be mistaken for 1µg. A large NRV percentage is a label calculation, not an absorption percentage.
A delivery instruction
Sprays, drops and dissolving tablets can be practical preferences. They are not presumed equivalent to an injection or inherently more effective than swallowed tablets.
| Context | What it means |
|---|---|
| Dietary requirement | NHS guidance gives about 1.5µg/day for adults aged 19–64. This is a nutritional requirement, not a treatment dose. |
| Label NRV | The B12 nutrient reference value is 2.5µg. It is used for label percentages: 1,000µg ÷ 2.5µg × 100 = 40,000%. It is not the proportion absorbed. UK reference-value table. |
| Vegan maintenance | The Vegan Society describes reliable fortified foods or a supplement supplying at least 10µg daily, or at least 2,000µg weekly. These are alternative maintenance approaches for normal absorption, not deficiency treatment. Frequency matters; a weekly dose is not simply interchangeable with its arithmetic daily average. |
| Retail serving | This table follows the confirmed adult label. It marks quarter-tablet servings and the chosen basis where a label permits a range. Dose and price/day always use the same basis. |
| Deficiency treatment | NHS cyanocobalamin medicine guidance describes 50–150µg daily for diet-related deficiency and different, sometimes much larger, prescribed doses for other causes. Treatment is chosen and monitored clinically; do not use the product ranking to set it. |
There is no universal “commonly studied range” badge for B12. A maintenance intake, a medicine dose and a high-strength retail formulation serve different purposes. “Lower-dose tablet” in our picks means 100µg/day or less within this comparison set; it is not an official range.
B12 supports normal blood-cell formation and nervous-system function. Correcting a deficiency is different from expecting additional energy when B12 status is already adequate. NIH ODS consumer overview.
Our provisional score reflects disclosed formulation, serving clarity, daily cost and manufacturer/label transparency. It measures neither absorbed B12 nor your likelihood of benefit. Detailed testing research is pending; a laboratory claim on Amazon is not verified evidence.
| Goal | Evidence strength | What was assessed | Typical study context | Main limitation |
|---|---|---|---|---|
| Correcting deficiency | Established clinical use | Oral or injected B12 chosen for the cause | Individual treatment and follow-up | Retail products cannot replace an assessment. |
| Vegan dietary adequacy | Established nutrition need | Reliable fortified foods or supplementation | Maintenance with normal absorption | Diet may not be the only reason for low B12. |
| Extra energy without deficiency | Benefit not established | Additional B12 in people with adequate status | Separate nutrition claims from symptom treatment | Tiredness has many possible causes. |
| Memory and cognition | No general benefit established | Supplementation beyond correcting deficiency | Studies differ in population and baseline status | A cognitive symptom needs assessment. |
| Sublingual or methylated superiority | No automatic advantage established | Oral delivery and disclosed B12 forms | Dose and study design affect comparisons | A seller claim does not establish clinical superiority. |
NIH ODS’s professional review finds no evidence that supplement absorption rates differ by B12 form, and no demonstrated efficacy difference between oral and sublingual preparations. The fraction absorbed falls at larger doses. We do not turn seller claims into multipliers.
Tiredness, a sore tongue or memory changes have several possible causes. B12 deficiency can also affect nerves without anaemia. NHS symptom guidance explains why persistent symptoms merit assessment.
NHS treatment guidance distinguishes dietary deficiency from absorption problems. Tablets or injections may be needed, sometimes long term. Continue an established treatment plan unless your clinician changes it.
Some products are swallowed with food; others dissolve under the tongue or are sprayed inside the cheek. Use the listed directions. Liquid droppers differ: eight drops on one product need not equal eight drops on another.
Choose a consistent time compatible with the directions; this comparison does not claim a universal best hour. Prescribed cyanocobalamin tablets are usually taken on an empty stomach, but that medicine instruction should not be imposed on every retail gummy or spray.
Shake or prime a spray where instructed. Follow storage and opened shelf-life rules. Declared bottle yield may be reduced by priming, spills or discarded expired liquid; it is not a guarantee of usable days.
The NHS says 2 mg (2,000µg) or less daily in supplements is unlikely to cause harm. This is safety context, not a target or a formal upper limit. NIH ODS reports no established tolerable upper intake level for B12; that does not show that ever-higher amounts add benefit.
Seek medical assessment for persistent unexplained symptoms, particularly numbness, pins and needles or balance changes. Untreated deficiency can cause lasting problems. NHS advice. Do not wait for a retail supplement to prove whether you are deficient.
MHRA guidance flags sensitivity reactions to hydroxocobalamin and cyanocobalamin medicines in people with cobalt allergy. Tell a pharmacist or prescriber about a known allergy; seek urgent help for a severe allergic reaction. Do not stop medically necessary treatment without advice.
Gummies may contain sugars; dissolving tablets and sprays may use polyols or flavourings. A vegan claim does not mean allergen-free. The full analysis records disclosed ingredients and where allergen information remains unknown.
The MHRA identifies reduced B12 as a common metformin side effect, with higher risk at larger doses and longer use. A clinician may arrange testing or monitoring. Continue metformin unless your prescriber advises otherwise.
Proton pump inhibitors and H2 blockers can affect B12 absorption from food. Tell your clinician what you take if investigating low B12; do not stop prescribed medication yourself. NIH ODS medicine interactions.
Folic acid treatment can obscure an underlying B12 deficiency while neurological problems remain. NHS guidance explains checking B12 before folate treatment. A B12/folate or B-complex product is not automatically necessary; compare added quantities across your supplements.
The Vegan Society recommends dependable fortified foods or supplements. Check plant milk, cereal and nutritional yeast labels: they are not all fortified. Unfortified plant foods should not be assumed to provide reliable B12.
Meat, fish, milk, cheese and eggs can provide B12. Fortified foods offer alternatives. NHS food guidance. A diet containing B12 does not rule out poor absorption.
A clinician considers symptoms, blood results and potential causes, including absorption problems. A low result is not automatically explained by a vegan diet; nor does a normal-looking result necessarily settle persistent symptoms. NHS diagnosis guidance.
If you are comparing other nutrients in a plant-based diet, the existing vitamin D and vegan omega-3 comparisons show their own dietary and formulation considerations.
A pending label means the product evidence review is unfinished. Brand statements about GMP, laboratory testing or certificates require checks against the relevant finished product and batch. Open each product’s current status and sources.
A useful report identifies the product, batch, laboratory, method, date and measured result. Ingredient identity and declared B12 content are different checks from microbiology or contaminants. A generic certificate need not establish this bottle’s potency.
Testing contributes no weight until researched. Remaining displayed weights use the existing rounded increments. No bonus is given merely for methylated forms, a higher µg headline, sublingual delivery or a blend with more ingredients.
| Context | What it means |
|---|---|
| Total B12 | Serum cobalamin; commonly reported in ng/L or pmol/L. It includes B12 bound to different blood proteins. |
| Active B12 | Holotranscobalamin, usually in pmol/L. This measures the fraction carried by transcobalamin; it is a different test from total B12. |
| MMA | Methylmalonic acid can help clarify an indeterminate B12 result when symptoms are present. Interpret it using the laboratory’s range and clinical context. |
| Folate and blood count | These help assess related deficiencies and blood-cell changes. A blood count alone cannot exclude B12 deficiency. NHS diagnostic context. |
NICE NG239 uses total or active B12 initially in most circumstances. Its indeterminate bands are total B12 180–350 ng/L (133–258 pmol/L), or active B12 25–70 pmol/L. These guide investigation, not self-diagnosis; validated local thresholds can differ.
A commercial blood test does not choose a dose or replace follow-up. Use the laboratory’s units and supplied range, and discuss unclear or discordant results with a clinician.
A testing claim is not the same as a verified report. No public evidence located does not mean a product has not been tested.
Current UK comparison set, based on the daily serving shown on each label.
Shown only where the underlying product data is reliable.
This page does not rank it automatically higher. Both are B12 forms; the evidence does not establish one best retail form for everyone. See the forms and evidence sections.
Yes. µg and mcg both mean micrograms; 1 mg equals 1,000µg. Dose and price/day use the same recorded label serving.
The label reference is 2.5µg. A 1,000µg serving is 40,000% of that reference; this is not an absorbed percentage or evidence that you need that amount.
The dose guide separates Vegan Society maintenance options from treatment of deficiency. Your diet, product frequency and absorption history matter; do not select a treatment dose from the comparison score.
They can be easier to use for some people, but this comparison gives no automatic absorption advantage. Follow the individual product’s mouth or tongue instructions.
Do not replace prescribed injections yourself. The reason for deficiency and any neurological involvement determine the clinical treatment plan.
Correcting deficiency can help deficiency-related symptoms. Extra energy in someone with adequate B12 is not established; unexplained tiredness deserves assessment.
Follow the pack or prescription. Retail directions vary; the NHS empty-stomach instruction for cyanocobalamin medicine is not a rule for every gummy or spray.
No. Symptoms can occur without anaemia. Total or active B12 and other tests may be considered alongside symptoms and medical history.
It can increase the measured level. Tell the clinician what you take and when you started; do not stop necessary treatment just to arrange a test.
No whole-product assumption is made from the vitamin form. Check the capsule, flavourings and stated dietary suitability. Unknown claims remain unknown here.
Listings with unresolved dose, ingredient or serving conflicts are held in draft. Missing values are not guessed, and pending testing is not labelled no public evidence.
Read our methodology and how we verify testing.